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Clinical Establishments Act: what it asks of a diagnostic lab

The Clinical Establishments (Registration and Regulation) Act, 2010 requires every lab in an adopting state to register, and since 2018 it has set minimum standards for diagnostic labs in three tiers: basic composite, medium and advanced. Below: whether it applies to you, how registration works, the full standards checklist, and who may sign a report. Each point is taken from the Act or the Gazette, not from a summary.

Checked against the Act and the Gazette · updated 26 September 2026 · free to print and share

Does it apply to your lab?

Yes, if your state has adopted it. Section 2(c)(ii) covers any place where pathological, bacteriological, genetic, radiological, chemical or biological investigations are carried on with laboratory equipment, standalone or inside a hospital or clinic.

Adopted in 19 States and UTs (central portal, 26 Sep 2026): Arunachal Pradesh, Assam, Bihar, Haryana, Himachal Pradesh, Jharkhand, Mizoram, Rajasthan, Sikkim, Telangana, Uttar Pradesh, Uttarakhand, and all Union Territories except the NCT of Delhi. Labs in Hyderabad fall under it, since Telangana is on the list. Other states regulate labs under their own laws.

What the Act says, section by section

s.2(c)(ii) Covers labs
A clinical establishment includes a place, independent or part of a hospital or clinic, where pathological, bacteriological, genetic, radiological, chemical, biological investigations or other diagnostic or investigative services are usually carried on with the aid of laboratory or other medical equipment.
s.11 Registration is mandatory
No person shall run a clinical establishment unless it has been duly registered under the Act.
s.12 Conditions
To register and stay registered, the establishment must meet the prescribed minimum standards of facilities and services, minimum personnel, and provisions for maintaining records and reporting.
s.14–15 Provisional registration
Apply in the prescribed form with the fee, in person, by post or online. The authority grants a provisional certificate within ten days, without prior inquiry (s.16).
s.17 Valid 12 months
A provisional registration is valid to the last day of the twelfth month from issue, and is renewable.
s.18 Display it
The certificate must be affixed in a conspicuous place, visible to everyone visiting the establishment.
s.23 Provisional has a time limit
Once standards for a category are notified, provisional registration cannot be granted or renewed beyond two years from notification for establishments that already existed, or six months for those set up after notification. Permanent registration then applies (s.24–30).
s.41 Penalty for running unregistered
Up to ₹50,000 for the first contravention, up to ₹2 lakh for the second, up to ₹5 lakh for any later one. Knowingly working in an unregistered establishment: up to ₹25,000.
s.43 Minor deficiencies
Deficiencies that pose no imminent danger to patients and can be put right in reasonable time: fine up to ₹10,000.

Which tier is your lab?

The 2018 Schedule sorts labs by the tests they run. A lab doing routine biochemistry, haemograms and urine routine is a basic composite lab; the tiers above add to it.

AreaBasic compositeMediumAdvanced
BiochemistryRoutine tests: blood sugar, renal and liver function, amylase, lipase, lipid profile, CSF and other fluids (glucose, protein), OGTT, electrolytes, calcium or phosphate, HbA1c, any biochemistry rapid testAdds hormone bioassay, tumour markers, plasma protein electrophoresisAdds coagulation profile, drug monitoring and toxicology, molecular genetics, inborn errors of metabolism
HaematologyHaemogram, bleeding time, clotting time, PT, APTT, blood grouping and matchingAdds coagulation assayAll other haematology tests
HistopathologyNoneMay do, subject to equipment and specialistHistopathology examination
Molecular geneticsNoneMay do, subject to equipment and specialistMolecular genetics
CytopathologyNonePAP smear, FNAC, sputum and CSF cytologyImmunocytochemistry, other fluid cytology, ultrasound- or CT-guided FNAC
ImmunohistopathologyNoneNoneImmunohistochemistry
Microbiology and immunologyRapid point-of-care tests for infection, urine routine and microscopy, hanging drop for V. cholerae, stool for ova and cyst. All HIV-positive rapid assays confirmed at the next-level labAdds serology for viruses, bacteria, fungi, parasites; bacterial or fungal culture sensitivity; special stains beyond Gram'sAdds viral culture sensitivity, RT-PCR, tissue diagnosis for infectious diseases

The minimum standards checklist

Checklist of minimum standards for diagnostic labs under the Clinical Establishments Act 2010, marking each requirement Essential or Desirable for basic composite, medium and advanced labs: signage, safety, space, staff, equipment, legal, records and processes
Print it for the lab. Every row is from the Schedule to rule 8A (G.S.R. 468(E), 18 May 2018); the table below gives the Gazette's full wording.

Signage

RequirementBasic compositeMediumAdvanced
Basic signage within or outside the facilityEssentialEssentialEssential
Name of the person in charge, with qualification and registration numberEssentialEssentialEssential
Broad services provided (haematology, biochemistry, clinical pathology, histology, cytology, molecular genetics, whichever apply)EssentialEssentialEssential
Timings of the different consultantsDesirableEssentialEssential
Internet facility, or telephone and mobile number for appointmentDesirableDesirableDesirable
Fee structure displayed separately, with the type of investigation and charges, special and routineEssentialEssentialEssential

Safety signage

RequirementBasic compositeMediumAdvanced
Safety hazard and caution signs; biomedical waste segregated in coloured bins and bags as per the BMW Rules 2016, including radioactive, toxic, microbial and infected materialEssentialEssentialEssential
Appropriate fire exit signage, minimum one fire extinguisherDesirableDesirableEssential

Space and fixtures

RequirementBasic compositeMediumAdvanced
Registration and waiting room, public utilities, safe drinking waterDesirableEssentialEssential
Sample collection areaEssentialEssentialEssential
Laboratory with adequate diffuse and spot lightingEssentialEssentialEssential
ToiletEssentialEssentialEssential
Reporting and billing areaEssentialEssentialEssential
Staff room and doctor's duty room, separate for men and women where 24-hour services are availableDesirableDesirableEssential
Washing roomEssentialEssentialEssential
Preservation of specimens and slidesEssentialEssentialEssential
Electrical facilitiesEssentialEssentialEssential
Temperature control for specialised equipment such as flow cytometry, chemiluminescence and ELISAEssentialEssentialEssential
Counselling room for HIV, essential if HIV testing is doneEssential (see note)Essential (see note)Essential (see note)
FNAC room for sample collectionDesirableDesirableDesirable
Dark room for immunofluorescenceNot requiredNot requiredEssential
Frozen section facilitiesNot requiredEssentialEssential
Furniture and fixtures (medium and advanced: as per scope of services)EssentialEssentialEssential
Wash basinsEssentialEssentialEssential

People

RequirementBasic compositeMediumAdvanced
Technical head or authorised signatory. Basic composite: MBBS desirable, and a registered MBBS is essential wherever results are interpreted or an opinion is given. Medium and advanced: MD or DNB in pathology, biochemistry, microbiology or laboratory medicine, or DCP, or MBBS with a PhD in one of those subjects, is essential. The authorised signatory is liable for the authenticity of the report.Desirable (see note)EssentialEssential
Laboratory technicians with DMLT, B.Sc. MLT, or M.Sc. biochemistry or microbiology from a recognised institution1 minimum2 minimum4 minimum
Support staff (laboratory assistant or attendant), with a salary roster, periodic health check-ups and staff vaccination1 minimum1 minimum2 minimum

Equipment

RequirementBasic compositeMediumAdvanced
List of minimum diagnostic equipment and instruments, with quantity, as per scope of servicesEssentialEssentialEssential
Sterilisation, such as a hot air oven or autoclaveEssentialEssentialEssential
Lists of reagents, consumables and disposablesEssentialEssentialEssential
Policy of annual or comprehensive maintenance contract, with equipment records (log books)DesirableDesirableDesirable

Legal

RequirementBasic compositeMediumAdvanced
Registration under the Biomedical Waste Management Rules 2016 with the State Pollution Control Board, with registration number and expiry date; site, space, location and environment as per local bye-lawsEssentialEssentialEssential

Records

RequirementBasic compositeMediumAdvanced
Reports of all patients, date-wise and specialty-wise (for example histopathology, cytology, haematology, laboratory medicine)EssentialEssentialEssential
Medico-legal records, if applicable, as per relevant lawEssentialEssentialEssential
Records of technicians working in the laboratory, with their qualification and trainingEssentialEssentialEssential
Reference library: books, periodicals, e-journals or CDsDesirableDesirableDesirable
Duration of preservation of records, as applicable from time to timeEssentialEssentialEssential

Processes

RequirementBasic compositeMediumAdvanced
Infection control practices as per the BMW Rules 2016EssentialEssentialEssential
Safety considerations, such as the use of disposable needlesEssentialEssentialEssential
Patient information and educationEssentialEssentialEssential
Process of calibration of equipment and reagentsEssentialEssentialEssential
Booklet of standard operating procedures for all proceduresEssentialEssentialEssential
Grievance registration and disposal mechanismEssentialEssentialEssential
Quality control through an external quality assurance scheme or inter-laboratory comparisonDesirableDesirableDesirable
Policy of proficiency testing of tests performedDesirableDesirableDesirable

Who may sign a lab report

The 2018 standards: medium and advanced labs need an MD or DNB in pathology, biochemistry, microbiology or laboratory medicine, a DCP, or an MBBS with a PhD in one of those subjects. Biopsies and cytology are reported by an MD or DNB in pathology. For a basic composite lab an MBBS is desirable, and a registered MBBS is essential wherever results are interpreted. The authorised signatory is liable for the authenticity of the report.

The Medical Council of India's Board of Governors, 3 February 2020:

  • A technical report that states test results without any medical opinion can be signed by a person with an M.Sc. in medical biochemistry or medical microbiology, or a Ph.D. in a relevant subject such as biochemistry, microbiology, biotechnology or genetics.
  • Every report signed by such a person must carry a disclaimer that it is strictly for the use of medical practitioners and is not a medical diagnosis.
  • A laboratory report that contains a medical diagnosis or a medical opinion must be signed by a medically qualified professional registered as per the IMC Act.

Clinical Establishments Act: common questions

Does the Clinical Establishments Act apply to a diagnostic lab?

Yes, in the states that have adopted it. Section 2(c)(ii) of the Act includes any place where pathological, bacteriological, genetic, radiological, chemical or biological investigations are carried on with laboratory equipment, whether it stands alone or sits inside a hospital or clinic.

Which states have adopted the Clinical Establishments Act?

As listed on the central portal on 26 September 2026: Arunachal Pradesh, Assam, Bihar, Haryana, Himachal Pradesh, Jharkhand, Mizoram, Rajasthan, Sikkim, Telangana, Uttar Pradesh, Uttarakhand, and all Union Territories except the NCT of Delhi, 19 States and UTs in all. Other states regulate labs under their own laws.

What is the penalty for running a lab without registration?

Under section 41, up to ₹50,000 for the first contravention, up to ₹2 lakh for the second and up to ₹5 lakh for any later one. Anyone who knowingly works in an unregistered establishment can be fined up to ₹25,000.

Who can sign a laboratory report?

Under the 2018 standards, medium and advanced labs need an MD or DNB in pathology, biochemistry, microbiology or laboratory medicine, a DCP, or an MBBS with a PhD in one of those subjects. For a basic composite lab an MBBS is desirable, and essential wherever results are interpreted. The MCI Board of Governors added in February 2020 that an M.Sc. or Ph.D. holder may sign a technical report of results with a "not a medical diagnosis" disclaimer, but any report containing a diagnosis or medical opinion must be signed by a registered medical practitioner.

How long is provisional registration valid?

Twelve months from the date of issue, and renewable (section 17). Once standards for a category are notified, provisional registration cannot be renewed beyond two years from notification for labs that already existed, or six months for labs opened after it (section 23). Permanent registration then applies.

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